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anal glands and transitional zone epithelium are ck7 ck20-, different from colorectal carcinoma (ck7- ck20, arch pathol lab med 20011251074) notes ganglion cells are normally absent 1 - 2 cm above dentate line (important for hirschsprungs disease biopsies) multinucleated stromal cells are common (may be fibroblasts). The anal glands or anal sacs are small glands near the anus in many mammals, including dogs and cats. They are paired sacs on either side of the anus between the external and internal sphincter muscles. Sebaceous glands within the lining secrete a liquid that is used for identification of members within a species. These sacs are found in many carnivorans, including wolves, bears, sea otters and kinkajous. A chemical study of the secretion of the anal glands of mephitis mephitiga (common skunk), with remarks on the physiological properties of this secretion. Alpha-methyl-quinoline as a constituent of the secretion of the anal glands of mephitis mephitica. Author information (1)department of colorectal surgery, singapore general hospital. Purpose this study was designed to investigate the histology of adult anal glands using conventional as well as immunochemical methods. Author achudhan karunaharamoorthy reviewer dimitrios mytilinaios md, phd last reviewed may 20, 2020 the anal canal is the last part of the gastrointestinal tract. It is about 3 to 4 cm long and lies completely extraperitoneally. It begins at the anorectal junction distally from the perineal flexure and ends at the anus. purpose this study was designed to investigate the histology of adult anal glands using conventional as well as immunochemical methods. Methods fifteen fresh human ani were prepared and stained with conventional and immunohistologic stains. Results the median number of anal glands in each anus was six (range, 310). Features adenocarcinoma within the anal wall but not within the mucosa, i. The anal glands are modified tubuloalveolar sweat glands occupying the submocosa of the columnar and intermediate zones of the anal canal (dogs cats, pigs). Anal sac disease is the most common disease entity of the anal region in dogs. Small breeds are predisposed large or giant breeds are rarely affected. Apocrine gland adenocarcinomas of the anal sac are typically seen in older female dogs. Canine apocrine gland anal sac adenocarcinoma (agasaca) apocrine gland anal sac adenocarcinomas (agasaca) are malignant tumors of the anal glands. These are paired glands located on either side of the rectal opening. Anal glands are sweat glands that contain a brown, malodorous liquid that is eliminated upon defecation.